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Crohn's disease

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Radiologic tests[ edit ] A small bowel follow-through may suggest the diagnosis of Crohn's disease and is useful when the disease involves only the small intestine. The granulomas of Crohn's disease do not show "caseation", a cheese-like appearance on microscopic examination characteristic of granulomas associated with infections, such as tuberculosis.

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Erythrocyte sedimentation rate ESR and C-reactive protein help assess the degree of inflammation, which is important as ferritin can also be raised in inflammation. Biopsies may also show chronic mucosal damage, as evidenced by blunting of the intestinal villi , atypical branching of the crypts, and a change in the tissue type metaplasia. Finding a patchy distribution of disease, with involvement of the colon or ileum, but not the rectum , is suggestive of Crohn's disease, as are other endoscopic stigmata.

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3 Responses

  1. Doujora says:

    Gastroduodenal Crohn's disease causes inflammation in the stomach and first part of the small intestine, called the duodenum. These neutrophils, along with mononuclear cells , may infiltrate the crypts , leading to inflammation crypititis or abscess crypt abscess.

  2. Yorg says:

    They remain useful for identifying anatomical abnormalities when strictures of the colon are too small for a colonoscope to pass through, or in the detection of colonic fistulae in this case contrast should be performed with iodate substances.

  3. Mur says:

    In some cases, however, it may not be possible to tell the difference, in which case the disease is classified as indeterminate colitis.

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